At least, the play should have been negated, as Houston linebacker Jadeveon Clowney was clearly offsides on the play in which Bengals quarterback Andy Dalton threw a pick-6 to cornerback Johnathan Joseph.
H/T to our own Joe Goodberry for catching this
That play came in the third quarter with Cincinnati leading 16-3, and it shifted the momentum into the favor of the Texans, as they went on to tack on a field goal on their ensuing drive, leaving the Bengals with a slim 16-13 lead.
That kind of play simply can't be missed by the refs, but in the same breath, Dalton cannot make that kind of throw, even if he knew he had a free play with Clowney offsides. It could have ultimately cost the Bengals in a game they had to have to keep pace in the AFC North.